HCID 67536381, compound → HCID 87653511, compound

Participants

Reaction Steps

The title compound II-aq was prepared in 80% yield from 3,3:17,17-bis(ethylendioxy)-5α-hydroxy-6-(E)-hydroxyiminoandrostane by the procedure described above for the preparation of 6-methyleneandrostane-3,17-dione (I-ac, Prepn. 13). The combined organic extracts were washed with H2O, dried over Na2SO4 and evaporated to dryness. The residue was purified by flash chromatography (SiO2, n-hexane/acetone/CH2Cl2 60/20/20). 1H-NMR (300 MHz, acetone-d6, ppm from TMS: δ 10.72 (1H, s), 5.35 (1H, s), 3.12 (1H, dd), 2.85-1.09 (18H, m), 0.94 (3H, s), 0.78 (3H, s).

Provenance & Evidence