Benzenamine, 3,5-bis(trifluoromethyl)- → HCID 10025419, compound

HRID 421050Notes

Reaction equation

HRID 421050 reaction equation
[C:1]([C:3]([C:15]#[N:16])=[CH:4][C:5]1[CH:6]=[CH:7][C:8]([OH:14])=[C:9]([CH:13]=1)[C:10]([OH:12])=O)#[N:2].[F:17][C:18]([F:31])([F:30])[C:19]1[CH:20]=[C:21]([CH:23]=[C:24]([C:26]([F:29])([F:28])[F:27])[CH:25]=1)[NH2:22]>>[F:17][C:18]([F:30])([F:31])[C:19]1[CH:20]=[C:21]([NH:22][C:10](=[O:12])[C:9]2[CH:13]=[C:5]([CH:4]=[C:3]([C:1]#[N:2])[C:15]#[N:16])[CH:6]=[CH:7][C:8]=2[OH:14])[CH:23]=[C:24]([C:26]([F:27])([F:29])[F:28])[CH:25]=1

Participants

3

Reactant 2

HCID 9480Benzenamine, 3,5-bis(trifluoromethyl)-HCID 157071045-(2,2-Dicyanoethenyl)-2-hydroxybenzoic acid

Product 1

HCID 10025419HCID 10025419, compoundYield 9.1%

Procedure

Using 5-(2,2-dicyanoethen-1-yl)-2-hydroxybenzoic acid and 3,5-bis(trifluoromethyl)aniline as the raw materials, the same operation as the example 16 gave the title compound.

Sources & evidence

ORD record
ord-b7a92fe0a6fd40518f6dc908c2f626d1
Source dataset
uspto-grants-2012_01
Patent number
US08097759B2

Reaction notes

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