Benzenamine, 3,5-bis(trifluoromethyl)- → HCID 11754305, compound

HRID 421058Notes

Reaction equation

HRID 421058 reaction equation
[OH:1][C:2]1[CH:10]=[CH:9][C:8]([C:11]([F:17])([F:16])[C:12]([F:15])([F:14])[F:13])=[CH:7][C:3]=1[C:4]([OH:6])=O.[F:18][C:19]([F:32])([F:31])[C:20]1[CH:21]=[C:22]([CH:24]=[C:25]([C:27]([F:30])([F:29])[F:28])[CH:26]=1)[NH2:23]>>[F:18][C:19]([F:31])([F:32])[C:20]1[CH:21]=[C:22]([NH:23][C:4](=[O:6])[C:3]2[CH:7]=[C:8]([C:11]([F:17])([F:16])[C:12]([F:15])([F:14])[F:13])[CH:9]=[CH:10][C:2]=2[OH:1])[CH:24]=[C:25]([C:27]([F:28])([F:30])[F:29])[CH:26]=1

Participants

3

Reactant 2

HCID 9480Benzenamine, 3,5-bis(trifluoromethyl)-HCID 17860171HCID 17860171, compound

Product 1

HCID 11754305HCID 11754305, compound

Procedure

Using 2-hydroxy-5-(pentafluoroethyl)benzoic acid and 3,5-bis(trifluoromethyl)aniline as the raw materials, the same operation as the example 16 gave the title compound. (2-Hydroxy-5-(pentafluoroethyl)benzoic acid: refer to Chem. Pharm. Bull., 1996, 44, 734.)

Sources & evidence

ORD record
ord-4062dd21a71f446dab5f29ae36ce1c6c
Source dataset
uspto-grants-2012_01
Patent number
US08097759B2

Reaction notes

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