2-Thiopheneboronic acid → HCID 10320520, compound

HRID 421060Notes

Reaction equation

HRID 421060 reaction equation
[F:1][C:2]([F:25])([F:24])[C:3]1[CH:4]=[C:5]([NH:13][C:14](=[O:23])[C:15]2[CH:20]=[C:19](I)[CH:18]=[CH:17][C:16]=2[OH:22])[CH:6]=[C:7]([C:9]([F:12])([F:11])[F:10])[CH:8]=1.[S:26]1[CH:30]=[CH:29][CH:28]=[C:27]1B(O)O>>[F:1][C:2]([F:25])([F:24])[C:3]1[CH:4]=[C:5]([NH:13][C:14](=[O:23])[C:15]2[CH:20]=[C:19]([C:27]3[S:26][CH:30]=[CH:29][CH:28]=3)[CH:18]=[CH:17][C:16]=2[OH:22])[CH:6]=[C:7]([C:9]([F:12])([F:11])[F:10])[CH:8]=1

Participants

3

Reactant 2

HCID 27339602-Thiopheneboronic acidHCID 11190699N-[3,5-bis(trifluoromethyl)phenyl]-2-hydroxy-5-iodo-benzamide

Product 1

HCID 10320520HCID 10320520, compound

Procedure

Using N-[3,5-bis(trifluoromethyl)phenyl]-2-hydroxy-5-iodobenzamide and 2-thipheneboronic acid as the raw materials, the same operation as the example 69 gave the title compound.

Sources & evidence

ORD record
ord-8997389af3944266b5257ebc4a4aaf93
Source dataset
uspto-grants-2012_01
Patent number
US08097759B2

Reaction notes

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