Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 421094Generated: October 25, 2026

5-Chlorosalicylic Acid → 5-Chloro-N-[2-fluoro-3-(trifluoromethyl)phenyl]-2-hydroxybenzamide

https://huagongshe.com/reaction/421094

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Chlorosalicylic AcidHCID 9447—
Reactant3-Amino-2-fluorobenzotrifluorideHCID 145569—
Product5-Chloro-N-[2-fluoro-3-(trifluoromethyl)phenyl]-2-hydroxybenzamideHCID 1786016171.7%

Reaction Steps

Using 5-chlorosalicylic acid and 2-fluoro-3-(trifluoromethyl)aniline as the raw materials, the same operation as the example 16 gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08097759B2
Source datasetuspto-grants-2012_01
ORD IDord-4b7aa17251374474a1f68ee68498a675
Source noteuspto-grants-2012_01