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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 421098Generated: October 25, 2026

5-Chlorosalicylic Acid → 5-Chloro-N-[2-fluoro-5-(trifluoromethyl)phenyl]-2-hydroxybenzamide

https://huagongshe.com/reaction/421098

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Chlorosalicylic AcidHCID 9447—
Reactant2-Fluoro-5-(trifluoromethyl)anilineHCID 136349—
Product5-Chloro-N-[2-fluoro-5-(trifluoromethyl)phenyl]-2-hydroxybenzamideHCID 1786016377.9%

Reaction Steps

Using 5-chlorosalicylic acid and 2-fluoro-5-(trifluoromethyl)aniline as the raw materials, the same operation as the example 16 gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08097759B2
Source datasetuspto-grants-2012_01
ORD IDord-34e4c2a491384e10a600cfff19bea5ed
Source noteuspto-grants-2012_01