5-Bromosalicylic acid → HCID 17860117, compound

HRID 421100Notes

Reaction equation

HRID 421100 reaction equation
[Br:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[Cl:12][C:13]1[CH:19]=[CH:18][C:17]([C:20]([F:23])([F:22])[F:21])=[CH:16][C:14]=1[NH2:15]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:15][C:14]1[CH:16]=[C:17]([C:20]([F:21])([F:22])[F:23])[CH:18]=[CH:19][C:13]=1[Cl:12])=[O:9]

Participants

3

Reactant 2

HCID 69725-Bromosalicylic acidHCID 8475Benzenamine, 2-chloro-5-(trifluoromethyl)-

Product 1

HCID 17860117HCID 17860117, compoundYield 34.2%

Procedure

Using 5-bromosalicylic acid and 2-chloro-5-(trifluoromethyl)aniline as the raw materials, the same operation as the example 16 gave the title compound.

Sources & evidence

ORD record
ord-d2ff1d083d374f9faf95fde86a96e017
Source dataset
uspto-grants-2012_01
Patent number
US08097759B2

Reaction notes

Loading…