5-Bromosalicylic acid → HCID 10408035, compound

HRID 421108Notes

Reaction equation

HRID 421108 reaction equation
[Br:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[CH3:12][O:13][C:14]1[CH:15]=[C:16]([CH:18]=[C:19]([C:21]([F:24])([F:23])[F:22])[CH:20]=1)[NH2:17]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:17][C:16]1[CH:18]=[C:19]([C:21]([F:23])([F:24])[F:22])[CH:20]=[C:14]([O:13][CH3:12])[CH:15]=1)=[O:9]

Participants

3

Reactant 2

HCID 69725-Bromosalicylic acidHCID 6056715-(Trifluoromethyl)-m-anisidine

Product 1

HCID 10408035HCID 10408035, compoundYield 58.8%

Procedure

Using 5-bromosalicylic acid and 3-methoxy-5-(trifluoromethyl)aniline as the raw materials, the same operation as the example 16 gave the title compound.

Sources & evidence

ORD record
ord-1318f95e5a374bcf93c73e5abaa9a4d4
Source dataset
uspto-grants-2012_01
Patent number
US08097759B2

Reaction notes

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