Acetyl chloride → HCID 17860120, compound

HRID 421114Notes

Reaction equation

[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([OH:22])=[C:6]([CH:21]=1)[C:7]([NH:9][C:10]1[CH:15]=[C:14]([C:16]([F:19])([F:18])[F:17])[CH:13]=[CH:12][C:11]=1[Cl:20])=[O:8].[C:23](Cl)(=[O:25])[CH3:24]>>[C:23]([O:22][C:5]1[CH:4]=[CH:3][C:2]([Cl:1])=[CH:21][C:6]=1[C:7]([NH:9][C:10]1[CH:15]=[C:14]([C:16]([F:17])([F:19])[F:18])[CH:13]=[CH:12][C:11]=1[Cl:20])=[O:8])(=[O:25])[CH3:24]

Participants

Reactant 2

HCID 6367Acetyl chloride

HCID 17860267HCID 17860267, compound

Product 1

HCID 17860120HCID 17860120, compoundYield 34%

Procedure

Using 5-chloro-N-[2-chloro-5-(trifluoromethyl)phenyl]-2 hydroxybenzamide and acetyl chloride as the raw materials, the same operation as the example 96 gave the title compound.

Sources & evidence

ORD record: ord-721000bc5faa49aea2d3a5a6545d9146
Source dataset: uspto-grants-2012_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08097759B2

Reaction notes

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