5-Bromosalicylic acid → 5-bromo-N-(3,4-dichlorophenyl)-2-hydroxybenzamide

HRID 421125Notes

Reaction equation

HRID 421125 reaction equation
[Br:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[Cl:12][C:13]1[CH:14]=[C:15]([CH:17]=[CH:18][C:19]=1[Cl:20])[NH2:16]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:16][C:15]1[CH:17]=[CH:18][C:19]([Cl:20])=[C:13]([Cl:12])[CH:14]=1)=[O:9]

Participants

3

Reactant 2

HCID 69725-Bromosalicylic acidHCID 72573,4-Dichloroaniline

Product 1

HCID 52713095-bromo-N-(3,4-dichlorophenyl)-2-hydroxybenzamideYield 58.2%

Procedure

Using 5-bromosalicylic acid and 3,4-dichloroaniline as the raw materials, the same operation as the example 16 gave the title compound.

Sources & evidence

ORD record
ord-79ff0721ff3a43208d87dce8558af3de
Source dataset
uspto-grants-2012_01
Patent number
US08097759B2

Reaction notes

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