5-Bromosalicylic acid → HCID 17860206, compound

HRID 421126Notes

Reaction equation

HRID 421126 reaction equation
[Br:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[F:12][C:13]1[CH:14]=[C:15]([CH:17]=[C:18]([F:20])[CH:19]=1)[NH2:16]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:16][C:15]1[CH:14]=[C:13]([F:12])[CH:19]=[C:18]([F:20])[CH:17]=1)=[O:9]

Participants

3

Reactant 2

HCID 69725-Bromosalicylic acidHCID 965953,5-Difluoroaniline

Product 1

HCID 17860206HCID 17860206, compoundYield 36.3%

Procedure

Using 5-bromosalicylic acid and 3,5-difluoroaniline as the raw materials, the same operation as the example 16 gave the title compound.

Sources & evidence

ORD record
ord-9f7b287888b04ab8ade2cd6dd0cd2e26
Source dataset
uspto-grants-2012_01
Patent number
US08097759B2

Reaction notes

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