5-Bromosalicylic acid → 5-Bromo-N-(3,5-dimethoxyphenyl)-2-hydroxybenzamide

HRID 421147Notes

Reaction equation

HRID 421147 reaction equation
[Br:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[CH3:12][O:13][C:14]1[CH:15]=[C:16]([CH:18]=[C:19]([O:21][CH3:22])[CH:20]=1)[NH2:17]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:17][C:16]1[CH:18]=[C:19]([O:21][CH3:22])[CH:20]=[C:14]([O:13][CH3:12])[CH:15]=1)=[O:9]

Participants

3

Reactant 2

HCID 69725-Bromosalicylic acidHCID 663013,5-Dimethoxyaniline

Product 1

HCID 178601215-Bromo-N-(3,5-dimethoxyphenyl)-2-hydroxybenzamideYield 40.3%

Procedure

Using 5-bromosalicylic acid and 3,5-dimethoxyaniline as the raw materials, the same operation as the example 16 gave the title compound.

Sources & evidence

ORD record
ord-66981f5771044fe49eff3bbb46e511fa
Source dataset
uspto-grants-2012_01
Patent number
US08097759B2

Reaction notes

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