3'-Aminoacetophenone → HCID 17860178, compound

HRID 421148Notes

Reaction equation

[Cl:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[C:12]([C:15]1[CH:16]=[C:17]([CH:19]=[CH:20][CH:21]=1)[NH2:18])(=[O:14])[CH3:13]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:18][C:17]1[CH:19]=[CH:20][CH:21]=[C:15]([C:12](=[O:14])[CH3:13])[CH:16]=1)=[O:9]

Participants

Reactant 2

HCID 74173'-Aminoacetophenone

HCID 94475-Chlorosalicylic Acid

Product 1

HCID 17860178HCID 17860178, compoundYield 80%

Procedure

Using 5-chlorosalicylic acid and 3-acetylaniline as the raw materials, the same operation as the example 16 gave the title compound.

Sources & evidence

ORD record: ord-eaac0798e886438c85bd311f27eb2138
Source dataset: uspto-grants-2012_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08097759B2

Reaction notes

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