5-Bromosalicylic acid → HCID 17860155, compound

HRID 421162Notes

Reaction equation

HRID 421162 reaction equation
[Br:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[NH2:12][C:13]1[S:14][C:15]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)=[C:16]([CH2:18][CH3:19])[N:17]=1>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:12][C:13]1[S:14][C:15]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)=[C:16]([CH2:18][CH3:19])[N:17]=1)=[O:9]

Participants

3

Reactant 2

HCID 69725-Bromosalicylic acidHCID 13914690HCID 13914690, compound

Product 1

HCID 17860155HCID 17860155, compoundYield 17.4%

Procedure

Using 5-bromosalicylic acid and 2-amino-4-ethyl-5-phenylthiazole as the raw materials, the same operation as the example 16 gave the title compound.

Sources & evidence

ORD record
ord-b83f4dbaa09649cbb2d63c5951bc7738
Source dataset
uspto-grants-2012_01
Patent number
US08097759B2

Reaction notes

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