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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 421177Generated: October 26, 2026

Ethyl 2-amino-4-phenyl-1,3-thiazole-5-carboxylate → 2-[2-Hydroxy-5-(1-pyrrolyl)benzoyl]amino-4-phenylthiazole-5-carboxylic acid ethyl ester

https://huagongshe.com/reaction/421177

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-amino-4-phenyl-1,3-thiazole-5-carboxylateHCID 73239—
Reactant2-Hydroxy-5-(1H-pyrrol-1-yl)benzoic acidHCID 853752—
Product2-[2-Hydroxy-5-(1-pyrrolyl)benzoyl]amino-4-phenylthiazole-5-carboxylic acid ethyl esterHCID 1004849355%

Reaction Steps

Using 2-hydroxy-5-(1-pyrrolyl)benzoic acid and 2-amino-4-phenylthiazole-5-carboxylic acid ethyl ester as the raw materials, the same operation as the example 195(3) gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08097759B2
Source datasetuspto-grants-2012_01
ORD IDord-a122a864a547498e8ea6613f3e562c4d
Source noteuspto-grants-2012_01