HRID42118

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：C=C1C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)CCC(=O)CC12

HCID67536381

未命名化合物

结构：C[C@]12CCCCC1C[C@@H](CO)[C@@H]1[C@@H]2CC[C@@]2(C)[C@H]1CC13OCCOC12OCCO3

HCID86635588

未命名化合物

PRODUCTS

生成物

结构：C[C@]12CCC(=O)CC1C[C@@H](CO)[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12

HCID69007745

未命名化合物

收率 85%

PROCEDURE

实验过程

7α-Hydroxymethylandrostane-3,17-dione II-av was prepared in 85% yield from 3,3:17,17-bis(ethylendioxy)-7α-hydroxymethyl-androstane by the procedure described above for the preparation of 6-methyleneandrostane-3,17-dione (I-ac, Prepn. 13). The combined organic extracts were washed with H2O, dried over Na2SO4 and evaporated to dryness. 1H-NMR (300 MHz, acetone-d6, ppm from TMS): δ 3.71 (2H, m), 3.30 (1H, t), 2.50-1.25 (21H, m), 1.12 (3H, s), 0.85 (3H, s).

WORKUP

后处理

washThe combined organic extracts were washed with H2O
dry with materialdried over Na2SO4
customevaporated to dryness