HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(tert-Butoxycarbonyl)-4-piperidinecarboxylic acid → 3beta-(N-(tert-Butoxycarbonyl)piperidin-4-ylcarbonyloxy)androstane-6,17-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(tert-Butoxycarbonyl)-4-piperidinecarboxylic acid | HCID 392871 | — |
| Reactant | 3beta-Hydroxy-5alpha-androstan-6,17-dione | HCID 69012642 | — |
| Product | 3beta-(N-(tert-Butoxycarbonyl)piperidin-4-ylcarbonyloxy)androstane-6,17-dione | HCID 69007552 | 62% |
Reaction Steps
Prepared in 62% yield from 3β-hydroxyandrostane-6,17-dione and 1-(tert-butoxycarbonyl)-4-piperidinecarboxylic acid by the procedure described in Prepn. 43. 1H-NMR (300 MHz, DMSO-d6, ppm from TMS): δ 4.65 (1H, m), 3.60-1.20 (29H, m), 1.35 (9H, s), 0.78 (3H, s), 0.69 (3H, s).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08536160B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-1d14a398c4934b3d94989ff830c09e66 |
| Source note | uspto-grants-2013_09 |