HCID 67083260, compound → HCID 44819977, compound

Participants

Reaction Steps

To a solution of tert-butyl 4-[2-(4-methanesulfonylbenzyloxy)pyridin-5-yl]-3,6-dihydro-2H-pyridine-1-carboxylate (Example 6) (39 mg, 87.7 μmol) in methanol (2 mL) was added 10% platinum-carbon (15 mg). The mixture was hydrogenated at room temperature for 17 hours and filtered through Celite pad. The filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (hexane/ethyl acetate=1/1) to give the title compound as a white crystal (20 mg, yield 51%).

Provenance & Evidence