1-(Methylsulfonyl)piperazine → HCID 11634899, compound

HRID 421628Notes

Reaction equation

HRID 421628 reaction equation
Cl[C:2]1[N:3]=[C:4]([N:22]2[CH2:27][CH2:26][O:25][CH2:24][CH2:23]2)[C:5]2[S:10][C:9]([CH2:11][N:12]3[CH2:17][CH2:16][N:15]([S:18]([CH3:21])(=[O:20])=[O:19])[CH2:14][CH2:13]3)=[CH:8][C:6]=2[N:7]=1.CS(N1[CH2:37][CH2:36][NH:35][CH2:34][CH2:33]1)(=O)=O>>[NH:35]1[C:36]2[C:37](=[C:4]([C:2]3[N:3]=[C:4]([N:22]4[CH2:27][CH2:26][O:25][CH2:24][CH2:23]4)[C:5]4[S:10][C:9]([CH2:11][N:12]5[CH2:17][CH2:16][N:15]([S:18]([CH3:21])(=[O:20])=[O:19])[CH2:14][CH2:13]5)=[CH:8][C:6]=4[N:7]=3)[CH:5]=[CH:6][CH:8]=2)[CH:33]=[CH:34]1

Participants

3

Reactant 2

HCID 7091611-(Methylsulfonyl)piperazineHCID 236508374-(2-Chloro-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)thieno[3,2-d]pyrimidin-4-yl)morpholine

Product 1

HCID 11634899HCID 11634899, compound

Procedure

Via 2-Chloro-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine, prepared from 1-methanesulfonyl-piperazine

Sources & evidence

ORD record
ord-b26b1b3bfd654989b0e9a6a125977a4f
Source dataset
uspto-grants-2012_01
Patent number
US08101607B2

Reaction notes

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