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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 421675Generated: October 26, 2026

4-Fluorobenzoic Acid → HCID 16730640, compound

https://huagongshe.com/reaction/421675

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorobenzoic AcidHCID 9973—
ReactantN-(3-amino-4-chlorophenyl)-2-methyl-6-(trifluoromethyl)nicotinamideHCID 16730560—
ProductHCID 16730640HCID 16730640—

Reaction Steps

N-(3-amino-4-chlorophenyl)-2-methyl-6-(trifluoromethyl)nicotinamide (0.15 mmol) was used in general procedure 2 with 4-fluorobenzoic acid (0.167 mmol). The product was purified by RP-HPLC to give N-(4-chloro-3-(4-fluorobenzamido)phenyl)-2-methyl-6-(trifluoromethyl)-nicotinamide. MS (Q1) 452.0 (M)+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08101610B2
Source datasetuspto-grants-2012_01
ORD IDord-8cee007d74834ad4bb29c4740f3b5a7f
Source noteuspto-grants-2012_01