HCID 11992504, compound → HCID 11992608, compound

Participants

Reaction Steps

2,2-Dimethylpropyl 4-(4-nitropyridin-2-yl)-1-piperazinecarboxylate (482 mg) obtained in Example 8 was dissolved in methanol (10 mL), and a catalytic amount of palladium hydroxide-carbon was added thereto, stirred in a hydrogen atmosphere at room temperature for 2 hours, and the reaction liquid was filtered. The filtrate was evaporated, and the resulting residue was isolated and purified through thin-layer silica gel chromatography (chloroform/methanol=19/1) to obtain 48 mg of the entitled compound as an oil.

Provenance & Evidence