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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 421918Generated: October 27, 2026

2-Fluoro-4-(methylsulfanyl)aniline → Methyl 2-(2-fluoro-4-(methylthio) phenylamino)-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate

https://huagongshe.com/reaction/421918

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-4-(methylsulfanyl)anilineHCID 22025617—
ReactantMethyl 2-chloro-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylateHCID 57442171—
ProductMethyl 2-(2-fluoro-4-(methylthio) phenylamino)-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylateHCID 66673753—

Reaction Steps

Methyl 2-(2-fluoro-4-(methylthio)phenylamino)-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate was prepared from methyl 2-chloro-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate and 2-fluoro-4-(methylthio)benzenamine as described in Step C of Example 153.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08101611B2
Source datasetuspto-grants-2012_01
ORD IDord-268008f876dd41e984237db633d8cc36
Source noteuspto-grants-2012_01