Triethylamine → 1-(3-nitro-phenyl)-3-(2-oxo-2,3-dihydro-1H-indol-6-yl)-urea

Participants

Reaction Steps

To a solution of 6-amino-1,3-dihydro-indol-2-one (0.15 g, 1.0 mmol) and triethylamine (0.30 g, 3.0 mmol) in THF (10 ml) is added 1-isocyanato-3-nitro-benzene (0.16 g, 1.0 mmol). The reaction is stirred at room temperature for 1 hour and the precipitate is collected by vacuum filtration and washed with ethanol to give the desired compound as a light yellow solid. LC-MS: 313.1 (MH+).

Provenance & Evidence