HuagongsheHuagongshe Chemistry Print Report · For research reference only
[2-Nitro-3-(3-nitro-phenylamino)-phenyl]-acetic acid ethyl ester → [2-Amino-3-(3-amino-phenylamino)-phenyl]-acetic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [2-Nitro-3-(3-nitro-phenylamino)-phenyl]-acetic acid ethyl ester | HCID 59804286 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | [2-Amino-3-(3-amino-phenylamino)-phenyl]-acetic acid ethyl ester | HCID 59804307 | — |
Reaction Steps
To a solution of [2-nitro-3-(3-nitro-phenylamino)-phenyl]-acetic acid ethyl ester (0.62 g, 1.8 mmol) in ethanol (50 ml) is added Pd/C (10%, wet, 0.50 g). It is placed under a hydrogen balloon and stirred for 20 hours. The catalyst is filtered and the solvent is removed to give the desired compound: LC-MS: 286.1 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08101608B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-d525e89864114f1f89bf883ef3009cc7 |
| Source note | uspto-grants-2012_01 |