反应详情

To a solution of [2-nitro-4-(3-nitro-phenoxy)-phenyl]-acetic acid ethyl ester (496 mg, 1.4 mmol) in acetic acid (5 mL) is added 10% Pd/C (48 mg). The mixture is stirred under hydrogen (balloon) overnight. The catalyst is filtered off and the solvent is evaporated to dryness. The crude product is purified by column chromatography (EtOAc/Hexane=9:1) to give 120 mg of the desired product (yield 50%). LC/MS: 242.2 (MH+).

1. filtrationThe catalyst is filtered off
2. customthe solvent is evaporated to dryness
3. customThe crude product is purified by column chromatography (EtOAc/Hexane=9:1)