methyl 2-(prop-2-en-1-yloxy)benzoate → HCID 136070706, compound

Participants

Reaction Steps

Using the same or analogous synthetic techniques described in Example 1, Using the same or analogous synthetic techniques described in Example 1, 6-[2-(butyloxy)phenyl]-4-(4-hydroxy-3-methylphenyl)pyrimidin-2-(1H)-one was prepared by replacing methyl 2-{[2-(methyloxy)ethyl]oxy}benzoate with methyl 2-(prop-2-en-yloxy)benzoate prepared according to Eissenstat, Michael A.; Bell, Malcolm R.; D'Ambra, Thomas E.; Alexander, E. John; Daum, Sol J.; Ackerman, James H.; Gruett, Monte D.; Kumar, Virendra; Estep, Kimberly G.; et al. Aminoalkylindoles: Structure-Activity Relationships of Novel Cannabinoid Mimetics. Journal of Medicinal Chemistry (1995), 38(16), 3094-105.

Provenance & Evidence