3-Butyn-1-OL → 2-(but-3-ynyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

Beteiligte Stoffe

Reaktionsschritte

The title compound was prepared in accordance with the general method of Example 109(D), from [1,2,4]triazolo[4,3-a]pyridin-3(2H)-one (405 mg, 3.00 mmol) and but-3-yn-1-ol (200 mg, 2.85 mmol). The crude residue was purified by flash chromatography (DCM/MeOH 99:1) to yield 140 mg (0.75 mmol, 26%) of 2-(but-3-ynyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one.

Herkunft & Nachweise