HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromopyridine → HCID 11579841, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromopyridine | HCID 7973 | — |
| Reactant | HCID 86086914 | HCID 86086914 | — |
| Product | HCID 11579841 | HCID 11579841 | 52% |
Reaction Steps
The title compound was prepared in accordance with the general method of Example 1, from 2-bromopyridine (107 mg, 0.68 mmol) and 2-(but-3-ynyl)-7-fluorobenzo[d]oxazole (128 mg, 0.68 mmol). The crude residue was purified by flash chromatography (DCM/MeOH 99:1) to yield 94 mg (0.35 mmol, 52%) of 7-fluoro-2-(4-(pyridin-2-yl)but-3-ynyl)benzo[d]oxazole as a brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08101637B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-abe7b12a49e947538392fc0e64041d12 |
| Source note | uspto-grants-2012_01 |