反应详情

According to the general protocol for oxadiazole synthesis described in Example 40(C) the conversion of 3-chloro-N′-hydroxy-2-methylbenzidine (628 mg, 3.4 mmol) afforded 387 mg of 5-(but-3-ynyl)-3-(3-chloro-2-methylphenyl)-1,2,4-oxadiazole (Yield: 46%) as yellow oil.