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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 422303Generated: October 31, 2026

2-Bromopyridine → HCID 11687442, compound

https://huagongshe.com/reaction/422303

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-BromopyridineHCID 7973—
ReactantHCID 86086739HCID 86086739—
ProductHCID 11687442HCID 11687442—
Product(1,3)Oxazolo(5,4-b)pyridineHCID 19831830—

Reaction Steps

The title compound was prepared in accordance with the general method of Example 1, from 2-bromopyridine (92 mg, 0.58 mmol) and 2(but-3-ynyl)oxazolo[5,4-b]pyridine (100 mg, 0.58 mmol). The crude residue was purified by flash chromatography (DCM/MeOH 98.5:1.5 to 98:2) to yield 56 mg (0.22 mmol, 39%) of 2-(4-pyridin-2-yl)but-3-ynyl)oxazolo[5,4-b]pyridine as a colorless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08101637B2
Source datasetuspto-grants-2012_01
ORD IDord-37e51a1ff0d045719310e83b101bcafc
Source noteuspto-grants-2012_01