2-Bromopyridine → HCID 11587474, compound

Participants

Reaction Steps

The title compound was prepared in accordance with the general method of Example 1, from 2-bromopyridine (157 mg, 1.00 mmol) and pent-4-ynoic acid (2-chloro-phenyl)-methyl-amide (220 mg, 1.00 mmol). The crude residue was purified by flash chromatography (DCM/MeOH 98:2) to yield 20 mg (66 μmol 7%) of N-(2-chlorophenyl-N-methyl-5-(pyridin-2-yl)pent-4-ynamide as a brown liquid.

Provenance & Evidence