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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 422353Generated: October 31, 2026

2-Bromopyridine → HCID 66597879, compound

https://huagongshe.com/reaction/422353

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-BromopyridineHCID 7973—
ReactantHCID 86086766HCID 86086766—
ProductHCID 66597879HCID 6659787911.2%

Reaction Steps

The title compound was prepared in accordance with the general method of Example 1, from 2-bromopyridine (66 mg, 0.42 mmol) and 2-but-3-ynyl-7-chloro-4-fluoro-benzo[d]thiazole (100 mg, 0.42 mmol). The crude residue was purified by flash chromatography (cyclohexane/AcOEt 7:3) to yield 15 mg (47 μmol, 11%) of 7-chloro-4-fluoro-2-(4-(pyridin-2-yl)but-3-ynyl)benzo[d]thiazole as a brown oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08101637B2
Source datasetuspto-grants-2012_01
ORD IDord-db2809e782694211b142d7860a14ca90
Source noteuspto-grants-2012_01