HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromopyridine → HCID 66597894, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromopyridine | HCID 7973 | — |
| Reactant | 5-Hexyn-1-ol | HCID 70234 | — |
| Product | HCID 66597894 | HCID 66597894 | 78% |
Reaction Steps
The title compound was prepared in accordance with the general method of Example 1, from 2-bromopyridine (6.44 g, 40.8 mmol) and hex-5-yn-1-ol (4.00 g, 40.8 mmol). The crude residue was purified by flash chromatography (DCM/MeOH 1:1) to yield 5.56 g (31.7 mmol, 78%) of 6-pyridin-2-yl-hex-5-yn-1-ol as an orange oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08101637B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-b98c616c5c7e4c6cadfb808e350c6ba5 |
| Source note | uspto-grants-2012_01 |