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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 422504Generated: October 30, 2026

Benzoyl Peroxide → Methyl 2-(bromomethyl)benzoate

https://huagongshe.com/reaction/422504

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzoyl PeroxideHCID 7187—
ReactantMethyl o-toluateHCID 33094—
ReactantN-bromobutanimideHCID 67184—
ProductMethyl 2-(bromomethyl)benzoateHCID 273481392.2%

Reaction Steps

A solution of methyl-2-methylbenzoate (250 mg, 1.66 mmol), NBS (296 mg, 1.66 mmol) and dibenzoylperoxide (403 mg, 1.66 mmol) was stirred under reflux for one day. After purification by flash chromatography, 350 mg (1.53 mmol, 92%) of methyl-2-(bromomethyl)benzoate were obtained as a colorless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08101637B2
Source datasetuspto-grants-2012_01
ORD IDord-d631deca23a344b7baee6a9665977bb5
Source noteuspto-grants-2012_01