HCID 59261368, compound → HCID 59726029, compound

HRID 422566Notes

Reaction equation

HRID 422566 reaction equation
[CH3:1][C:2]1[CH:16]=[CH:15][C:5]([C:6]([NH:8][C:9]2[N:13]([CH3:14])[N:12]=[CH:11][CH:10]=2)=[O:7])=[CH:4][C:3]=1B1OC(C)(C)C(C)(C)O1.Cl[C:27]1[CH:28]=[C:29]2[C:34](=[CH:35][CH:36]=1)[C:33]([C:37]1([C:40]([F:43])([F:42])[F:41])[CH2:39][CH2:38]1)=[N:32][N:31]=[CH:30]2>>[CH3:1][C:2]1[CH:16]=[CH:15][C:5]([C:6]([NH:8][C:9]2[N:13]([CH3:14])[N:12]=[CH:11][CH:10]=2)=[O:7])=[CH:4][C:3]=1[C:27]1[CH:28]=[C:29]2[C:34](=[CH:35][CH:36]=1)[C:33]([C:37]1([C:40]([F:43])([F:42])[F:41])[CH2:39][CH2:38]1)=[N:32][N:31]=[CH:30]2

Participants

3

Reactant 2

HCID 59261368HCID 59261368, compoundHCID 666751956-Chloro-1-[1-(trifluoromethyl)cyclopropyl]phthalazine

Product 1

HCID 59726029HCID 59726029, compound

Procedure

The title compound was prepared according to a procedure analogous to that described in Example 225, using 4-methyl-N-(1-methyl-1H-pyrazol-5-yl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide and 6-chloro-1-(1-(trifluoromethyl)cyclopropyl)phthalazine as the starting materials. MS (ESI, pos. ion) m/z: 452.2 (M+1).

Sources & evidence

ORD record
ord-8574f8277d964c7c9061076caa8d7cc4
Source dataset
uspto-grants-2012_01
Patent number
US08101612B2

Reaction notes

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