HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178500928, compound → Methyl 1,6-dihydro-4-hydroxy-6-oxo-1-phenyl-3-pyridazinecarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178500928 | HCID 178500928 | — |
| Solvent | 1,2-Dichlorobenzene | HCID 7239 | — |
| Product | Methyl 1,6-dihydro-4-hydroxy-6-oxo-1-phenyl-3-pyridazinecarboxylate | HCID 54686161 | 99.1% |
Reaction Steps
A mixture of 3-oxo-2-(phenylhydrazono)-pentanedioic acid dimethyl ester (4.38 g, 15.7 mmol) in 1,2-dichlorobenzene (15 mL) was refluxed. After 20 hours, the reaction mixture was concentrated under reduced pressure to give 3.83 g (99%) of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08101639B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-4d11eac0e23b43b1886115f08898fabc |
| Source note | uspto-grants-2012_01 |