HCID 66675207, compound → HCID 66673945, compound

Participants

Reaction Steps

8-Fluoro-5-[1-(3-nitro-phenyl)-propylidene]-5,11-dihydro-10-oxa-1-aza-dibenzo[a,d]cycloheptene (1.49 g, 3.96 mmol) is dissolved in ethanol (20 mL) and purged with nitrogen. Pd/C (0.15 g, 10%) is added and the mixture hydrogenated under 1 atm of hydrogen for 2 h. The mixture is purged with nitrogen, filtered though Celite®, and the solids are washed with ethanol. The filtrate is concentrated under reduced pressure to obtain 1.37 g (99%) of the title compound. LCMS m/e 347 [M+H]+.

Provenance & Evidence