反应详情

温度

90 °C

To 250 ml of acetic acid, diluted with 130 ml of water, are added: 1.5 g of sodium nitrite, 0.13 mole of 2,5-dibromo-N-benzenesulphonylaniline prepared in the previous stage and 0.78 mole (32.5 ml) of nitric acid (d=1.52). The reaction mixture is heated for 1 hour at 90° C. The reaction mixture, cooled beforehand, is poured onto 1 kg of ice and the expected product precipitates. It is filtered off, washed to neutrality and then recrystallized from acetic acid; it melts at 148° C.

1. additionare added
2. temperatureThe reaction mixture, cooled beforehand
3. customthe expected product precipitates
4. filtrationIt is filtered off
5. washwashed to neutrality
6. customrecrystallized from acetic acid