反应详情

15 ml of water are added, with due care, to 115 ml of concentrated sulphuric acid; the temperature rises to 70° C. 0.105 mole (46 g) of 2,5-dibromo-4-nitro-N-benzenesulphonylaniline are then added. The temperature is maintained at 70°-78° C. for 2 hours. The reaction mixture is poured into 1 kg of ice and water; the expected product precipitates. After filtration and washing to neutrality the product is recrystallized from 450 ml of ethanol. It melts at 178° C.

1. customrises to 70° C
2. temperatureThe temperature is maintained at 70°-78° C. for 2 hours
3. customthe expected product precipitates
4. filtrationAfter filtration
5. washwashing to neutrality the product
6. customis recrystallized from 450 ml of ethanol