HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 42330Generated: October 29, 2026
HCID 58275259, compound → HCID 58275500, compound
https://huagongshe.com/reaction/42330
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 58275259 | HCID 58275259 | — |
| Reactant | HCID 58275351 | HCID 58275351 | — |
| Reactant | HCID 58275354 | HCID 58275354 | — |
| Reactant | HCID 58275379 | HCID 58275379 | — |
| Reactant | HCID 58275476 | HCID 58275476 | — |
| Reactant | HCID 67161822 | HCID 67161822 | — |
| Reactant | HCID 67162433 | HCID 67162433 | — |
| Reactant | HCID 67162584 | HCID 67162584 | — |
| Reactant | HCID 67163129 | HCID 67163129 | — |
| Reactant | HCID 67163310 | HCID 67163310 | — |
| Reactant | 4-{[6-(4-Fluoro-phenyl)-4-(1-trifluoromethyl-cyclopropylamino)-pyrido[3,2-d]pyrimidin-2-ylamino]-methyl}-2-trifluoromethyl-benzenesulfonamide | HCID 86653614 | — |
| Reactant | 4-{[6-(4-Fluoro-phenyl)-4-(1-trifluoromethyl-cyclopropylamino)-pyrido[3,2-d]pyrimidin-2-ylamino]-ethyl}-2-trifluoromethyl-benzenesulfonamide | HCID 86653615 | — |
| Reactant | HCID 86653616 | HCID 86653616 | — |
| Reactant | HCID 86653617 | HCID 86653617 | — |
| Product | HCID 58275500 | HCID 58275500 | — |
Reaction Steps
4-{[6-(4-Fluoro-phenyl)-4-(1-trifluoromethyl-cyclopropylamino)-pyrido[3,2-d]pyrimidin-2-ylamino]-methyl}-3-trifluoromethyl-benzenesulfonamide; 2-Chloro-4-{[6-(4-fluoro-phenyl)-4-(1-trifluoromethyl-cyclopropylamino)-pyrido[3,2-d]pyrimidin-2-ylamino]-methyl}-benzenesulfonamide; 2-Fluoro-4-{[6-(4-fluoro-phenyl)-4-(1-trifluoromethyl-cyclopropylamino)-pyrido[3,2-d]pyrimidin-2-ylamino]-methyl}-benzenesulfonamide; 2-Chloro-4-{1-[6-(4-fluoro-phenyl)-4-(1-trifluoromethyl-cyclopropylamino)-pyrido[3,2-d]pyrimidin-2-ylamino]-ethyl}-benzenesulfonamide; 2-Fluoro-4-{[6-(4-fluoro-phenyl)-4-(1-trifluoromethyl-cyclopropylamino)-pyrido[3,2-d]pyrimidin-2-ylamino]-ethyl}-benzenesulfonamide; 2-Chloro-5-{[6-(4-fluoro-phenyl)-4-(1-trifluoromethyl-cyclopropylamino)-pyrido[3,2-d]pyrimidin-2-ylamino]-methyl}-benzenesulfonamide; 3-Fluoro-5-{[6-(4-fluoro-phenyl)-4-(1-trifluoromethyl-cyclopropylamino)-pyrido[3,2-d]pyrimidin-2-ylamino]-methyl}-benzenesulfonamide; 4-{[6-(4-Fluoro-phenyl)-4-(1-trifluoromethyl-cyclopropylamino)-pyrido[3,2-d]pyrimidin-2-ylamino]-methyl}-2-trifluoromethyl-benzenesulfonamide; 4-{[6-(4-Fluoro-phenyl)-4-(1-trifluoromethyl-cyclopropylamino)-pyrido[3,2-d]pyrimidin-2-ylamino]-ethyl}-2-trifluoromethyl-benzenesulfonamide; N-(2-Fluoro-5-{[6-(4-fluoro-phenyl)-4-(1-trifluoromethyl-cyclopropylamino)-pyrido[3,2-d]pyrimidin-2-ylamino]-methyl}-phenyl)-methanesulfonamide, N-(5-{[6-(4-Fluoro-phenyl)-4-(1-trifluoromethyl-cyclopropylamino)-pyrido[3,2-d]pyrimidin-2-ylamino]-methyl}-2-trifluoromethyl-phenyl)-methanesulfonamide; N-(2-Chloro-5-{[6-(4-fluoro-phenyl)-4-(1-trifluoromethyl-cyclopropylamino)-pyrido[3,2-d]pyrimidin-2-ylamino]-methyl}-phenyl)-methanesulfonamide; N-(3-Chloro-5-{[6-(4-fluoro-phenyl)-4-(1-trifluoromethyl-cyclopropylamino)-pyrido[3,2-d]pyrimidin-2-ylamino]-methyl}-phenyl)-methanesulfonamide; N-(3-{[6-(4-Fluoro-phenyl)-4-(1-trifluoromethyl-cyclopropylamino)-pyrido[3,2-d]pyrimidin-2-ylamino]-methyl}-5-trifluoromethyl-phenyl)-methanesulfonamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08536187B2 |
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| Source dataset | uspto-grants-2013_09 |
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| ORD ID | ord-98d0c834dbde43a1b53db3864cf37fc4 |
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| Source note | uspto-grants-2013_09 |
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