HCID 58275390, compound → HCID 58275254, compound

HRID 42331Notes

Reaction equation

HRID 42331 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:9]=[CH:10][C:11]3[N:12]=[C:13]([NH:28][CH2:29][C:30]4[CH:35]=[CH:34][C:33]([S:36]([NH2:39])(=[O:38])=[O:37])=[CH:32][CH:31]=4)[N:14]=[C:15]([NH:18][C:19]4([C:24]([F:27])([F:26])[F:25])C[CH2:22][CH2:21][CH2:20]4)[C:16]=3[N:17]=2)=[CH:4][CH:3]=1.FC1C=CC(C2C=CC3N=C(NCC4C=CC(S(N)(=O)=O)=CC=4)N=C(NC4(C(F)(F)F)CCCCC4)C=3N=2)=CC=1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[CH:9]=[CH:10][C:11]3[N:12]=[C:13]([NH:28][CH2:29][C:30]4[CH:35]=[CH:34][C:33]([S:36]([NH2:39])(=[O:37])=[O:38])=[CH:32][CH:31]=4)[N:14]=[C:15]([NH:18][C:19]4([C:24]([F:27])([F:26])[F:25])[CH2:20][CH2:21][CH2:22]4)[C:16]=3[N:17]=2)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 58275390HCID 58275390, compoundHCID 58275431HCID 58275431, compound

Product 1

HCID 58275254HCID 58275254, compound

Procedure

4-{[6-(4-Fluoro-phenyl)-4-(1-trifluoromethyl-cyclopentylamino)-pyrido[3,2-d]pyrimidin-2-ylamino]-methyl}-benzenesulfonamide; 4-{[6-(4-Fluoro-phenyl)-4-(1-trifluoromethyl-cyclohexylamino)-pyrido[3,2-d]pyrimidin-2-ylamino]-methyl}-benzenesulfonamide.

Sources & evidence

ORD record
ord-f361ca36333847c5b8676d7e90545240
Source dataset
uspto-grants-2013_09
Patent number
US08536187B2

Reaction notes

Loading…