HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-bromobutanimide → HCID 10881860, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | N-tert-butyl-2-fluoro-4-methylbenzenesulfonamide | HCID 11107608 | — |
| Catalyst | Azobisisobutyronitrile | HCID 6547 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | HCID 10881860 | HCID 10881860 | 79.5% |
Reaction Steps
A mixture of N-tert-butyl-2-fluoro-4-methylbenzenesulfonamide (2 g), NBS (1.16 g) and AIBN (40 mg) in CCl4 (25 ml) was refluxed for 3 hours. The reaction mixture was cooled, filtered and concentrated to give a viscous syrup, which was purified by silica gel column chromatography to give 1.68 g 4-(bromomethyl)-N-tert-butyl-2-fluorobenzenesulfonamide as a colorless crystal solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08536187B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-de8c6aea1b5b471bb9a7eb52a9c13dc2 |
| Source note | uspto-grants-2013_09 |