HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromoethyl ethyl ether → 3-(2-Ethoxy-ethyl)-1H-indol-6-ylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromoethyl ethyl ether | HCID 61141 | — |
| Reactant | 6-Nitro-1H-indole | HCID 78502 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 3-(2-Ethoxy-ethyl)-1H-indol-6-ylamine | HCID 57470202 | — |
Reaction Steps
3-(2-Ethoxy-ethyl)-1H-indol-6-ylamine (B-16) was synthesized following the general scheme above starting from 6-nitroindole and 1-bromo-2-ethoxy-ethane. Overall yield (15%). HPLC ret. time 1.56 min, 10-99% CH3CN, 5 min run; ESI-MS 205.1 m/z (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08101767B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-6f772fff02b74548a73b22f69087103d |
| Source note | uspto-grants-2012_01 |