2-Fluoro-4-iodoaniline → 2,3-Difluoro-N-(2-fluoro-4-iodophenyl)-5-methyl-6-nitroaniline

HRID 424013Notes

Reaction equation

HRID 424013 reaction equation
[F:1][C:2]1[CH:8]=[C:7]([I:9])[CH:6]=[CH:5][C:3]=1[NH2:4].[F:10][C:11]1[CH:16]=[C:15]([CH3:17])[C:14]([N+:18]([O-:20])=[O:19])=[C:13](F)[C:12]=1[F:22]>>[F:22][C:12]1[C:11]([F:10])=[CH:16][C:15]([CH3:17])=[C:14]([N+:18]([O-:20])=[O:19])[C:13]=1[NH:4][C:3]1[CH:5]=[CH:6][C:7]([I:9])=[CH:8][C:2]=1[F:1]

Participants

3

Reactant 2

HCID 1856942-Fluoro-4-iodoanilineHCID 593863091,2,3-Trifluoro-5-methyl-4-nitrobenzene

Product 1

HCID 593863812,3-Difluoro-N-(2-fluoro-4-iodophenyl)-5-methyl-6-nitroaniline

Procedure

2-Fluoro-4-iodoaniline and 1,2,3-trifluoro-5-methyl-4-nitrobenzene were reacted using the condition described in Example 1 (Step A) to form the title compound. M−H+: 407.9

Sources & evidence

ORD record
ord-999ba65411c048bfb776953cc0e5e9e2
Source dataset
uspto-grants-2012_01
Patent number
US08101799B2

Reaction notes

Loading…