2-Bromo-4-fluorobenzoic acid → 2-Bromo-4-fluoro-1-(methoxymethoxymethyl)benzene

HRID 424367Notes

Reaction equation

HRID 424367 reaction equation
[Br:1][C:2]1[CH:10]=[C:9]([F:11])[CH:8]=[CH:7][C:3]=1[C:4](O)=[O:5].BrC1C=CC(Cl)=CC=1[CH2:20][O:21][CH2:22]OC>>[Br:1][C:2]1[CH:10]=[C:9]([F:11])[CH:8]=[CH:7][C:3]=1[CH2:4][O:5][CH2:20][O:21][CH3:22]

Participants

3

Reactant 2

HCID 12681692-Bromo-4-fluorobenzoic acidHCID 590246772-Bromo-5-chloro-1-(methoxymethoxymethyl)benzene

Product 1

HCID 667046952-Bromo-4-fluoro-1-(methoxymethoxymethyl)benzene

Procedure

This compound was made from 2-bromo-4-fluorobenzoic acid in the same manner as compound 18d and was used for the next step without purification.

Workup

  1. customwas used for the next step without purification

Sources & evidence

ORD record
ord-26cf496ab9514195b1fb5c9f9bcb4470
Source dataset
uspto-grants-2012_01
Patent number
US08106031B2

Reaction notes

Loading…