HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tavaborole → 5-Methyl-1,3-dihydro-2,1-benzoxaborol-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tavaborole | HCID 11499245 | — |
| Reactant | 2-Bromo-5-methyl-1-(methoxymethoxymethyl)benzene | HCID 59008782 | — |
| Product | 5-Methyl-1,3-dihydro-2,1-benzoxaborol-1-ol | HCID 11845749 | — |
Reaction Steps
This compound was made from 18e in the same manner as compound 19b: mp 124-128° C.; 1H NMR (300 MHz, DMSO-d6) δ (ppm) 2.33 (s, 3H), 4.91 (s, 2H), 7.13 (d, J=7.2 Hz, 1H), 7.18 (s, 1H), 7.58 (d, J=7.2 Hz, 1H), 9.05 (s, 1H); ESI-MS m/z 147 (M−H)−; HPLC purity 99.0%; Anal (C8HgBO2) C, H.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08106031B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-838b577167ae45c4ae179eda9e56e010 |
| Source note | uspto-grants-2012_01 |