HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tavaborole → 2,1-Benzoxaborole, 1,3-dihydro-1-hydroxy-5-methoxy-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tavaborole | HCID 11499245 | — |
| Reactant | 2-Bromo-5-methoxy-1-(methoxymethoxymethyl)benzene | HCID 66704987 | — |
| Product | 2,1-Benzoxaborole, 1,3-dihydro-1-hydroxy-5-methoxy- | HCID 11846117 | — |
Reaction Steps
This compound was made from 18g in the same manner as compound 19b: mp 102-104° C.; 1H NMR (300 MHz, DMSO-d6) δ (ppm) 3.77 (s,3H), 4.91 (s, 2H), 6.88 (d, J=8.1 Hz, 1H), 6.94 (s, 1H), 7.60 (d, J=8.1 Hz, 1H), 8.95 (s, 1H); ESI-MS m/z 163 (M−H)−; HPLC purity 100%; Anal (C8HgBO3) C, H.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08106031B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-7fe3c2e04e024b40b3d798b058631c95 |
| Source note | uspto-grants-2012_01 |