HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tavaborole → 5-(Hydroxymethyl)benzo[c][1,2]oxaborol-1(3h)-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tavaborole | HCID 11499245 | — |
| Reactant | 2-Bromo-1,5-bis(methoxymethoxymethyl)benzene | HCID 66704747 | — |
| Product | 5-(Hydroxymethyl)benzo[c][1,2]oxaborol-1(3h)-ol | HCID 11845751 | — |
Reaction Steps
This compound was made from 18h in the same manner as compound 19b: mp 124-128° C.; 1H NMR (300 MHz, DMSO-d6) δ (ppm) 4.53 (d, 2H), 4.94 (s, 2H), 5.24 (t, 1H), 7.26 (d, 1H), 7.33 (s, 1H), 7.64 (d, 1H), 9.08 (s, 1H); ESI-MS m/z 163 (M−H)−; HPLC purity 100%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08106031B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-e402c0c8508f4d01ab14c0db418536e4 |
| Source note | uspto-grants-2012_01 |