HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tavaborole → 6-Fluorobenzo[c][1,2]oxaborol-1(3H)-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tavaborole | HCID 11499245 | — |
| Reactant | 2-Bromo-4-fluoro-1-(methoxymethoxymethyl)benzene | HCID 66704695 | — |
| Product | 6-Fluorobenzo[c][1,2]oxaborol-1(3H)-ol | HCID 11846119 | — |
Reaction Steps
This compound was made from 18m in the same manner as compound 19b: 1H NMR (300 MHz, DMSO-d6) δ (ppm) 4.95 (s, 2H), 7.29 (td, J=9.0, 2.7 Hz, 1H), 7.41-7.46 (m, 2H), 9.29 (s, 1H); ESI-MS m/z 151 (M−H)−; HPLC purity 100%; Anal (C7H6BFO2) C, H.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08106031B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-5493b7950b6546aaa9ad4e19d8e78bea |
| Source note | uspto-grants-2012_01 |