HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → Cyclamen aldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | Hexane | HCID 8058 | — |
| Reactant | Diisobutylaluminumhydride | HCID 21225700 | — |
| Reactant | HCID 21862873 | HCID 21862873 | — |
| Solvent | Toluene | HCID 1140 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | Cyclamen aldehyde | HCID 517827 | — |
Reaction Steps
The acetal A can be reduced in a reduction reaction with a reducing agent, for example diisobutylaluminium hydride, sodium aluminium hydride or borane-THF complex, in diethyl ether, methylene chloride, THF, hexane, toluene or a mixture of the solvent mentioned, at a temperature of from −95° C. to −20° C. to give the aldehyde B.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08106055B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-00c7c7953afc4abe9ed3190a9570ea0a |
| Source note | uspto-grants-2012_01 |